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DoD Peer Reviewed Medical Research Program Clinical Trial Award

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Funding Opportunity Number: W81XWH-17-PRMRP-CTA 
Catalog of Federal Domestic Assistance Number: 12.420 Military Medical Research and Development

Submission and Review Dates and Times

  • Pre-Application Submission Deadline: 5:00 p.m. Eastern time (ET), July 20, 2017
  • Invitation to Submit an Application: August 2017
  • Application Submission Deadline: 11:59 p.m. ET, October 26, 2017
  • End of Application Verification Period: 5:00 p.m. ET, October 31, 2017
  • Peer Review: December 2017
  • Programmatic Review: February 2018 

Program Description 
Applications to the Fiscal Year 2017 (FY17) Peer Reviewed Medical Research Program (PRMRP) are being solicited for the Defense Health Agency (DHA) J9, Research and Development Directorate, by the U.S. Army Medical Research Acquisition Activity (USAMRAA) using delegated authority provided by United States Code, Title 10, Section 2358 (10 USC 2358). As directed by the Office of the Assistant Secretary of Defense for Health Affairs (OASD[HA]), the DHA manages the Defense Health Program (DHP) Research, Development, Test, and Evaluation (RDT&E) appropriation. The execution management agent for this Program Announcement is the Congressionally Directed Medical Research Programs (CDMRP). The PRMRP was initiated in 1999 to provide support for military health-related research of exceptional scientific merit. Appropriations for the PRMRP from FY99 through FY16 totaled $1.371 billion. The FY17 appropriation is $300 million (M).

The vision of the FY17 PRMRP is to improve the health and well-being of all military Service members, Veterans, and beneficiaries. The PRMRP challenges the scientific and clinical communities to address at least one of the FY17 Topic Areas with original ideas that foster new directions along the entire spectrum of research and clinical care. The program seeks applications in laboratory, clinical, behavioral, epidemiologic, and other areas of research to advance knowledge in disease etiology, improve prevention, detection, diagnosis, treatment, and quality of life for those affected by a relevant disease or condition, and to develop and validate clinical care or public health guidelines.

FY17 PRMRP Topic Areas 
All applications for PRMRP funding must specifically address at least one of the Topic Areas as directed by Congress and must be directly relevant to the healthcare needs of military Service members, Veterans, and/or beneficiaries. If the proposed research does not specifically address at least one of the FY17 PRMRP Topic Areas, the Government will administratively withdraw the application. The Government reserves the right to reassign the application’s Topic Area if submitted under an inappropriate Topic Area. The FY17 PRMRP Topic Areas are listed below.

  • Acute Lung Injury
  • Antimicrobial Resistance
  • Arthritis
  • Burn Pit Exposure
  • Chronic Migraine and Post-Traumatic Headache
  • Congenital Heart Disease
  • Constrictive Bronchiolitis
  • Diabetes
  • Diarrheal Diseases
  • Dystonia
  • Early Trauma Thermal Regulation
  • Eating Disorders
  • Emerging Infectious Diseases
  • Epidermolysis Bullosa
  • Focal Segmental Glomerulosclerosis
  • Fragile X
  • Guillain-Barré Syndrome
  • Hepatitis B and C
  • Hereditary Angioedema
  • Hydrocephalus
  • Immunomonitoring of Intestinal Transplants
  • Inflammatory Bowel Diseases
  • Influenza
  • Integrative Medicine
  • Interstitial Cystitis
  • Malaria
  • Metals Toxicology
  • Mitochondrial Disease
  • Musculoskeletal Disorders
  • Nanomaterials for Bone Regeneration
  • Non-Opioid Pain Management
  • Pancreatitis
  • Pathogen-Inactivated Dried Cryoprecipitate
  • Polycystic Kidney Disease
  • Post-Traumatic Osteoarthritis
  • Pulmonary Fibrosis
  • Respiratory Health
  • Rett Syndrome
  • Rheumatoid Arthritis
  • Scleroderma
  • Sleep Disorders
  • Spinal Muscular Atrophy
  • Sustained-Release Drug Delivery
  • Tinnitus
  • Tuberculosis
  • Vaccine Development for Infectious Disease
  • Vascular Malformations
  • Women’s Heart Disease 


Research relevant to one or more FY17 PRMRP Topic Areas may be considered for funding. Applicants should select the FY17 PRMRP Program Announcement most appropriate to the stage of the proposed research. Areas of Encouragement related to the FY17 PRMRP Topic Areas have been identified by the Department of Defense (DoD), the Department of Veterans Affairs (VA), and other relevant stakeholders (Appendix 2). Applicants are urged to read and consider these Areas of Encouragement before preparing their applications. The information provided is not exhaustive, and applicants are not restricted to submitting applications that address an Area of Encouragement in this list. 

For complete details about this opportunity, click here.  

Posting Information
This posting expired on July 21, 2017.

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