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Effect of Grapes Dietary Supplement on Brain Metabolism and Cognition

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Participants are sought who are experiencing problems with memory, communication skills, or general mental state. These changes could be the result of normal aging, or they could be early warning signs of developing dementia in the future. Through this study, we aim to determine whether grape consumption can affect brain metabolism and thinking abilities.

Eligible if:

  • Between age 65 and 84
  • Referred to the UCLA NeuroPET Clinics for concern of cognitive decline and/or behavioral changes

Not eligible if:

  • Have begun cholinesterase inhibitors or memantine in the last 6 months

Study involves:

  • 1 brain PET scan done initially and 1 brain PET scan 12 months later
  • General and neuropsychological assessments, done initially, 6 months later, and 12 months later
  • 12 months of adding grape powder to your diet (about 1 oz. twice a day)

Participants will receive up to $150 for the duration of study participation.

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